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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 501487Generated: October 29, 2026

4-(Trifluoromethyl)piperidine-1-carbonyl chloride → HCID 178429196, compound

https://huagongshe.com/reaction/501487

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)piperidine-1-carbonyl chlorideHCID 79887081—
ReactantHCID 178429276HCID 178429276—
ProductHCID 178429196HCID 178429196—

Reaction Steps

In analogy to example 12, 99.87 mg (0.344 mmol) of 6-hydroxy-4-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl 4-methylpiperidine-1-carboxylate were reacted with 83.4 mg (0.52 mmol) of 4-trifluoromethylpiperidine-1-carbonyl chloride. Yield: 16 mg (10%), M+H+: 470.20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772268B2
Source datasetuspto-grants-2010_08
ORD IDord-7abd77339cf14448ad2a3f785a3d3f8b
Source noteuspto-grants-2010_08