Sodium Iodide → 1-Iodoethyl ethyl carbonate

Temperature

60 °C

3.00 g of 1-chloroethyl ethyl carbonate was dissolved in 90 mL of acetonitrile, to which 13.3 g of sodium iodide was added, and this mixture was stirred for 1.5 hours at 60° C. This mixture was cooled to room temperature, followed by concentration thereof under reduced pressure, and then insoluble substances were filtered out thereof by adding diethyl ether to the residue. The resultant filtrate was concentrated under reduced pressure to yield 4.60 g of ethyl 1-iodoethyl carbonate as orange oil.

1. additionwas added
2. temperatureThis mixture was cooled to room temperature
3. concentrationfollowed by concentration
4. filtrationunder reduced pressure, and then insoluble substances were filtered out thereof
5. additionby adding diethyl ether to the residue
6. concentrationThe resultant filtrate was concentrated under reduced pressure

ORD record

ord-e861ee86b1ce4d22b553e758bbc6e963

Source dataset

uspto-grants-2010_08

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07772285B2