6-Bromo-4-(3-chlorophenyl)-2-methoxyquinoline → [4-(3-chloro-phenyl)-2-methoxy-quinolin-6-yl]-(6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanol

Participants

Role	Name	HCID	Charge
Reactant	6-Bromo-4-(3-chlorophenyl)-2-methoxyquinoline	HCID 12016672	—
Reactant	2-methyl-5-(1-methyl-1H-imidazole-5-carbonyl)pyridine	HCID 22465447	—
Product	[4-(3-chloro-phenyl)-2-methoxy-quinolin-6-yl]-(6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanol	HCID 18404110	48%

Reaction Steps

Following the same procedure as that described in Example 1E, 6-bromo-4-(3-chloro-phenyl)-2-methoxy-quinoline (0.200 g, 0.574 mmol) and (6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanone (0.105 g, 0.522 mmol) generated 0.118 g (48% yield) of [4-(3-chloro-phenyl)-2-methoxy-quinolin-6-yl]-(6-methyl-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanol.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06710209B2
Source dataset	uspto-grants-2004_03
ORD ID	ord-e1bffb28eceb4bcd9fcdf52f342a3580
Source note	uspto-grants-2004_03