反应详情

To 154.4 Kg isobutylamine, (1-Oxiranyl-2-phenyl-ethyl)-carbamic acid tert-butyl ester (53.3 Kg) was added, and then the solution was heated under reflux. Under reduced pressure, isobutylamine was removed from the reaction mixture, and then replaced by toluene.

1. temperaturethe solution was heated
2. temperatureunder reflux
3. customUnder reduced pressure, isobutylamine was removed from the reaction mixture