Hydrogen Peroxide → HCID 18412598, compound

HRID 50202Notes

Reaction equation

HRID 50202 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[N:6][C:7]([CH:11]=[O:12])=[CH:8][CH:9]=2)[N:4]=[C:3]1[CH2:13][O:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]#[N:22])=[CH:17][CH:16]=1.[OH:23]O>C(O)=O>[CH3:1][N:2]1[C:10]2[C:5](=[N:6][C:7]([C:11]([OH:23])=[O:12])=[CH:8][CH:9]=2)[N:4]=[C:3]1[CH2:13][O:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]#[N:22])=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 18412360HCID 18412360, compound

Product 1

HCID 18412598HCID 18412598, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

1.25 g (4.3 mmol) of 1-methyl-2-[(4-cyanophenyl)oxymethyl]imidazo[4,5-b]pyridine-5-carbaldehyde were dissolved in 10 mL formic acid and mixed at 0° C. with 1.0 mL hydrogen peroxide (33% strength). After 12 hours at 4° C., the white precipitate formed was suction filtered, washed with water, and dried at 40° C. Yield: 0.81 g (61% of theory), C16H12N4O3 (308.7).

Workup

  1. customthe white precipitate formed
  2. filtrationfiltered
  3. washwashed with water
  4. customdried at 40° C

Sources & evidence

ORD record
ord-7bdfff2d94fc4bf0b2fb7a245265f708
Source dataset
uspto-grants-2004_03
Patent number
US06710055B2

Reaction notes

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