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HRID50212

反应详情

EQUATION

反应方程式

HRID 50212 的结构方程式

REACTANTS

反应物

4
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CO
HCID887

Methanol

CH4O

结构：O=C([O-])[O-].[NH4+].[NH4+]
HCID517111

Ammonium carbonate

CH8N2O3

结构：COC(=O)CCN(C(=O)c1ccc2sc(CNc3ccc(C#N)cc3)nc2c1)c1ccccn1
HCID18412497

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)CCN(C(=O)c1ccc2sc(CNc3ccc(C(=N)N)cc3)nc2c1)c1ccccn1.Cl.Cl
HCID18412636

未命名化合物

收率 68%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(=O)O
催化剂HCID176

Acetic Acid

C2H4O2

结构：CCO.ClCCl
溶剂HCID21584144

Dichloromethane ethanol

C3H8Cl2O

PROCEDURE

实验过程

Prepared analogously to Example 9 from 2-[N-(4-cyanophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-methoxycarbonylethyl)amide, methanolic hydrochloric acid, methanol, and ammonium carbonate. Yield: 68% of theory, C25H24N6O3S (488.57); Rf value: 0.13 (silica gel; methylene chloride/ethanol=4:1+a few drops of acetic acid); EKA mass spectrum: (M+H)+=489.