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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 502344Generated: October 27, 2026

m-Anisoyl chloride → N-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-3-methoxy-benzamide

https://huagongshe.com/reaction/502344

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Anisoyl chlorideHCID 74374—
Reactant1-(4-Chloro-3-ethoxybenzyl)piperidin-4-ylamineHCID 59210377—
ProductN-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-3-methoxy-benzamideHCID 6845806565%

Reaction Steps

The title compound (26 mg, 65%) was prepared analogously to example 7 by coupling of 1-(4-chloro-3-ethoxy-benzyl)piperidin-4-ylamine with 3-methoxybenzoyl chloride. MS: 403.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772253B2
Source datasetuspto-grants-2010_08
ORD IDord-313f55fe0e6445b9b117b0ac4215181c
Source noteuspto-grants-2010_08