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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 502347Generated: November 3, 2026

p-Anisoyl chloride → N-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-4-methoxy-benzamide

https://huagongshe.com/reaction/502347

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Anisoyl chlorideHCID 7477—
Reactant1-(4-Chloro-3-ethoxybenzyl)piperidin-4-ylamineHCID 59210377—
ProductN-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-4-methoxy-benzamideHCID 6845492760%

Reaction Steps

The title compound (24 mg, 60%) was prepared analogously to example 7 by coupling of 1-(4-chloro-3-ethoxy-benzyl)piperidin-4-ylamine with 4-methoxybenzoyl chloride. MS: 403.4(MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772253B2
Source datasetuspto-grants-2010_08
ORD IDord-3b6c7d153d2e4ea595c917596eff95e9
Source noteuspto-grants-2010_08