HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethoxybenzoyl chloride → N-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-3,5-dimethoxy-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethoxybenzoyl chloride | HCID 87003 | — |
| Reactant | 1-(4-Chloro-3-ethoxybenzyl)piperidin-4-ylamine | HCID 59210377 | — |
| Product | N-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-3,5-dimethoxy-benzamide | HCID 68458525 | 56% |
Reaction Steps
The title compound (24 mg, 56%) was prepared analogously to example 7 by coupling of 1-(4-chloro-3-ethoxy-benzyl)piperidin-4-ylamine with 3,5-dimethoxybenzoyl chloride. MS: 433.5 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772253B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-588d530b4665408d8710ae2c890f2e73 |
| Source note | uspto-grants-2010_08 |