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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 502371Generated: November 2, 2026

Ethylvanillin → N-[1-(3-Ethoxy-4-hydroxy-benzyl)piperidin-4-yl]-5-methyl-nicotinamide

https://huagongshe.com/reaction/502371

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylvanillinHCID 8467—
Reactant5-Methyl-N-(piperidin-4-yl)-nicotinamideHCID 65562108—
ProductN-[1-(3-Ethoxy-4-hydroxy-benzyl)piperidin-4-yl]-5-methyl-nicotinamideHCID 68458774100%

Reaction Steps

The title compound (37 mg, 100%) was prepared analogously to example 30 from 5-methyl-N-(piperidin-4-yl)-nicotinamide and 3-ethoxy-4-hydroxy-benzaldehyde. MS: 370.5 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772253B2
Source datasetuspto-grants-2010_08
ORD IDord-8b794f83f60844de909f2355ca0972ba
Source noteuspto-grants-2010_08