Hydrochloric Acid → HCID 18412619, compound

HRID 50240Notes

Reaction equation

HRID 50240 reaction equation
[CH3:1][N:2]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[S:3]([C:6]1[CH:25]=[CH:24][C:9]2[N:10]([CH3:23])[C:11]([CH2:13][O:14][C:15]3[CH:20]=[CH:19][C:18]([C:21]#[N:22])=[CH:17][CH:16]=3)=[N:12][C:8]=2[CH:7]=1)(=[O:5])=[O:4].[ClH:32].C(O)C.C(=O)([O-])[O-].[NH4+:40].[NH4+]>CO>[ClH:32].[CH3:1][N:2]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[S:3]([C:6]1[CH:25]=[CH:24][C:9]2[N:10]([CH3:23])[C:11]([CH2:13][O:14][C:15]3[CH:16]=[CH:17][C:18]([C:21](=[NH:40])[NH2:22])=[CH:19][CH:20]=3)=[N:12][C:8]=2[CH:7]=1)(=[O:4])=[O:5]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 517111Ammonium CarbonateHCID 18412693HCID 18412693, compound

Product 1

HCID 18412619HCID 18412619, compoundYield 46%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared analogously to Example 32 from 1-methyl-2-[(4-cyanophenyl)oxymethyl]benzimidazol-5-yl-sulfonic acid-N-methyl-N-phenylamide and ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 46% of theory, C23H23N5O3S (449.5); EKA mass spectrum: (M+H)+=450; (M+H+methanol)+=482; (M+2H)++=223.

Sources & evidence

ORD record
ord-7f688a074dc1482ba50f7a120e19bdfd
Source dataset
uspto-grants-2004_03
Patent number
US06710055B2

Reaction notes

Loading…