Hydrochloric Acid → HCID 18412649, compound

HRID 50241Notes

Reaction equation

HRID 50241 reaction equation
[CH2:1]([O:3][C:4]([CH2:6][CH2:7][CH2:8][N:9]([C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)[S:10]([C:13]1[CH:32]=[CH:31][C:16]2[N:17]([CH3:30])[C:18]([CH2:20][O:21][C:22]3[CH:27]=[CH:26][C:25]([C:28]#[N:29])=[CH:24][CH:23]=3)=[N:19][C:15]=2[CH:14]=1)(=[O:12])=[O:11])=[O:5])[CH3:2].[ClH:39].C(=O)([O-])[O-].[NH4+:44].[NH4+]>C(O)C>[ClH:39].[CH2:1]([O:3][C:4]([CH2:6][CH2:7][CH2:8][N:9]([C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)[S:10]([C:13]1[CH:32]=[CH:31][C:16]2[N:17]([CH3:30])[C:18]([CH2:20][O:21][C:22]3[CH:27]=[CH:26][C:25]([C:28](=[NH:44])[NH2:29])=[CH:24][CH:23]=3)=[N:19][C:15]=2[CH:14]=1)(=[O:12])=[O:11])=[O:5])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 517111Ammonium CarbonateHCID 18412355HCID 18412355, compound

Product 1

HCID 18412649HCID 18412649, compoundYield 57%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 32 from 1-methyl-2-[(4-cyanophenyl)oxymethyl]benzimidazol-5-yl-sulfonic acid-N-(3-ethoxycarbonyl-n-propyl)-N-phenylamide, ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 57% of theory, C28H31N5O5S (549.7); EKA mass spectrum: (M+H)+=550.

Sources & evidence

ORD record
ord-566c2e6e31c54ff09cf483afad8ca026
Source dataset
uspto-grants-2004_03
Patent number
US06710055B2

Reaction notes

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