HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → n-Isopropyl-5-phenylfuro[2,3-d]pyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 4-Chloro-5-phenylfuro[2,3-d]pyrimidine | HCID 59427833 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | n-Isopropyl-5-phenylfuro[2,3-d]pyrimidin-4-amine | HCID 58603278 | — |
Reaction Steps
Into a 50 mL round bottom flask was placed 4-chloro-5-phenylfuro[2,3-d]pyrimidine, isopropanol (25 mL), and isopropylamine (1.5 g, 25 mmol). The flask was equipped with a magnetic stir bar, a reflux condenser, and argon balloon and the reaction was brought to reflux with stirring for 20 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07776867B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-f0d5b5a96a7b4505810185840659879b |
| Source note | uspto-grants-2010_08 |