反应详情

A solution of 27 (60 mg, 0.143 mmol), 2-(4-ethylpiperazin-1-yl)ethanamine (57 mg, 0.362 mmol), and DIEA (0.062 mL, 0.357 mmol) in CH2Cl2 (1 mL) and CH3CN (1 mL) was heated at 70° C. over night, then concentrated. Preparative TLC (SiO2, 20% MeOH in CH2Cl2) afforded the title compound 28. MS for C32H40N6O2: found 541 (M+H+), 539 (M−H+).

1. concentrationconcentrated