3-(Trifluoromethyl)aniline → 3-Bromo-4-fluoro-N-(3-(trifluoromethyl)phenyl)benzamide

HRID 502775노트

반응식

HRID 502775 반응식
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6].[Br:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[F:22])[C:16](Cl)=[O:17]>>[Br:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][C:21]=1[F:22])[C:16]([NH:6][C:5]1[CH:7]=[CH:8][CH:9]=[C:3]([C:2]([F:10])([F:11])[F:1])[CH:4]=1)=[O:17]

참가 물질

3

반응물 2

HCID 73753-(Trifluoromethyl)anilineHCID 695983-Bromo-4-fluorobenzoyl chloride

생성물 1

HCID 594280183-Bromo-4-fluoro-N-(3-(trifluoromethyl)phenyl)benzamide

실험 절차

3-Bromo-4-fluoro-N-(3-(trifluoromethyl)phenyl)benzamide was synthesized from 3-trifluoromethylaniline and 3-bromo-4-fluorobenzoyl chloride according to the procedure described in Example 183, affording the title compound as a white solid. MS (M−H+) 360.0; Calculated for C14H8BrF4NO: 361.

출처 및 근거

ORD 기록
ord-22dee11b126a415faf162fd1a70dc9da
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07776869B2

반응 노트

불러오는 중…