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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 502775Generated: October 25, 2026

3-(Trifluoromethyl)aniline → 3-Bromo-4-fluoro-N-(3-(trifluoromethyl)phenyl)benzamide

https://huagongshe.com/reaction/502775

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)anilineHCID 7375—
Reactant3-Bromo-4-fluorobenzoyl chlorideHCID 69598—
Product3-Bromo-4-fluoro-N-(3-(trifluoromethyl)phenyl)benzamideHCID 59428018—

Reaction Steps

3-Bromo-4-fluoro-N-(3-(trifluoromethyl)phenyl)benzamide was synthesized from 3-trifluoromethylaniline and 3-bromo-4-fluorobenzoyl chloride according to the procedure described in Example 183, affording the title compound as a white solid. MS (M−H+) 360.0; Calculated for C14H8BrF4NO: 361.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07776869B2
Source datasetuspto-grants-2010_08
ORD IDord-22dee11b126a415faf162fd1a70dc9da
Source noteuspto-grants-2010_08