HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 18412330, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 18412542 | HCID 18412542 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | HCID 18412330 | HCID 18412330 | 45% |
Reaction Steps
Prepared analogously to Example 26 from 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-fluorophenyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 45% of theory, C26H25FN6O3 (488.5); Rf value: 0.05 (silica gel; dichloromethane/ethanol=4:1); EKA mass spectrum: (M+H)+=489; (M+H+Na)++=267; (M+2H)++=256.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-6058597a919a42abb81710519912dc13 |
| Source note | uspto-grants-2004_03 |