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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 502953Generated: November 2, 2026

Methyl iodide → Methyl 1-(2-thienyl)cyclobutanecarboxylate

https://huagongshe.com/reaction/502953

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium BicarbonateHCID 516893—
Reactant1-(Thiophen-2-yl)cyclobutanecarboxylic acidHCID 23294887—
SolventDimethylformamideHCID 6228—
ProductMethyl 1-(2-thienyl)cyclobutanecarboxylateHCID 68467379—

Reaction Steps

1-(2-Thienyl)cyclobutanecarboxylic acid, methyl iodide, and potassium hydrogen carbonate were reacted in DMF at room temperature to obtain methyl 1-(2-thienyl)cyclobutanecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07776897B2
Source datasetuspto-grants-2010_08
ORD IDord-37af93649fd14a9aa76e4450f00e6ffd
Source noteuspto-grants-2010_08