Hydrochloric Acid → HCID 86616226, compound

Participants

Reaction Steps

An 1M aqueous sodium hydroxide solution (10 ml) of 2-{[1-(3-chloro-4-methyl-2-thienyl)cyclopentyl]carbonyl}-N-methylhydrazinecarbothioamide (167 mg) was refluxed for 20 hours. An 1M aqueous hydrochloric acid solution was added to the reaction solution to acidify the solution and precipitated crude crystals were collected by filtration and washed with water to obtain 154 mg of 5-[1-(3-chloro-4-methyl-2-thienyl)cyclopentyl]-4-methyl-2,4-dihydro-3H-1,2,4-triazol-3-thione (pale brown solid).

Provenance & Evidence