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HRID50352

反应详情

EQUATION

反应方程式

HRID 50352 的结构方程式

REACTANTS

反应物

4
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CCO
HCID702

Ethanol

C2H6O

结构：O=C([O-])[O-].[NH4+].[NH4+]
HCID517111

Ammonium carbonate

CH8N2O3

结构：Cn1c(CNc2ccc(C#N)cc2)nc2cc(C(=O)NCc3ccccc3)ccc21
HCID18412730

未命名化合物

PRODUCTS

生成物

1
结构：Cl.Cn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)NCc3ccccc3)ccc21
HCID18412608

未命名化合物

收率 63%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO.ClCCl
溶剂HCID21584144

Dichloromethane ethanol

C3H8Cl2O

PROCEDURE

实验过程

Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-benzylamide, ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 63% of theory, C24H24N6O (412.5); Rf value: 0.76 (silica gel; dichloromethane/ethanol=4:1); EKA mass spectrum: (M+H)+=413.