HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18412630, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | HCID 18412586 | HCID 18412586 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 18412630 | HCID 18412630 | 33% |
Reaction Steps
Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]-5-(isoindolin-2-yl-sulfonyl)benzimidazole and ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 33% of theory, C24H24N6O2S (460.6); Rf value: 0.32 (silica gel; dichloromethane/methanol=4:1); EKA mass spectrum: (M+H)+=461.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-fd0b2acc5681490d8b660217cf8dea09 |
| Source note | uspto-grants-2004_03 |