HRID50368

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)CCN(c1cnn(C)c1)S(=O)(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C.Cl

HCID18412489

未命名化合物

PRODUCTS

生成物

结构：Cn1cc(N(CCC(=O)O)S(=O)(=O)c2ccc3c(c2)nc(CNc2ccc(C(=N)N)cc2)n3C)cn1

HCID18412535

未命名化合物

收率 95%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Prepared analogously to Example 26 from 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-sulfonic acid-N-(1-methylpyrazol-4-yl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 95% of theory, C23H26N8O4S (510.6); Rf value: 0.53 (Reversed Phase silica gel RP-18, methanol+5% saline solution); EKA mass spectrum: (M+H)+=511; (M+Na)+=533; (M+2Na)++=278.