Potassium Hydroxide → HCID 85962067, compound

HRID 503682Notes

Reaction equation

HRID 503682 reaction equation
[CH3:1][S:2]([O:5][CH2:6][CH2:7][N:8]([CH2:25][CH2:26][O:27][S:28]([CH3:31])(=[O:30])=[O:29])[C:9]1[C:10]([N+:22]([O-:24])=[O:23])=[C:11]([C:16]([N+:19]([O-:21])=[O:20])=[CH:17][CH:18]=1)[C:12]([O:14]C)=[O:13])(=[O:4])=[O:3].[OH-].[K+]>O1CCOCC1>[CH3:31][S:28]([O:27][CH2:26][CH2:25][N:8]([CH2:7][CH2:6][O:5][S:2]([CH3:1])(=[O:4])=[O:3])[C:9]1[C:10]([N+:22]([O-:24])=[O:23])=[C:11]([C:16]([N+:19]([O-:21])=[O:20])=[CH:17][CH:18]=1)[C:12]([OH:14])=[O:13])(=[O:29])=[O:30]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 10791062HCID 10791062, compound

Product 1

HCID 85962067HCID 85962067, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Hydrolysis of 16 (10.6 g, 21.9 mmol) with 3 N KOH (40 mL) in dioxane (200 mL) at room temperature for 15 min, followed by acidification with 1 N HCl and extraction with EtOAc, gave a quantitative yield of crude 3-(bis{2-[(methylsulfonyl)oxy]ethyl}amino)-2,6-dinitrobenzoic acid (17):

Workup

  1. extractionfollowed by acidification with 1 N HCl and extraction with EtOAc

Sources & evidence

ORD record
ord-ef93097ce9ce4c5db8f7bbf8c294893a
Source dataset
uspto-grants-2010_08
Patent number
US07776924B2

Reaction notes

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