HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-bromobutanimide → 4-(3-Bromo-6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-bromobutanimide | HCID 67184 | — |
| Edukt | 4-(6-Phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde | HCID 86630655 | — |
| Lösungsmittel | Chloroform | HCID 6212 | — |
| Produkt | 4-(3-Bromo-6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde | HCID 86630658 | — |
Reaktionsschritte
1.5 g 4-(6-phenylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde (prepared as described under example 1) and 0.9 g NBS are refluxed in 30 ml chloroform for 1 h. The solvent is removed by distillation and the crude product is purified by column chromatography (dichloromethane/methanol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07776864B2 |
| Quelldatensatz | uspto-grants-2010_08 |
| ORD ID | ord-37feae7cdef94c4984893af73bece249 |
| Quellennotiz | uspto-grants-2010_08 |