反应详情

温度

0 °C

100 mg of the product of step 1 are dissolved in dichloromethane, cooled to 0° C. and 86 mg PBr3 are added. The mixture is stirred at room temperature for 24 h. Ice is added, the mixture extracted with dichloromethane and water, the organic layer are dried over Na2SO4 and the solvent is evaporated.

1. additionIce is added
2. extractionthe mixture extracted with dichloromethane and water
3. dry with materialthe organic layer are dried over Na2SO4
4. customthe solvent is evaporated