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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 503960Generated: November 4, 2026

Trifluoroacetic acid → HCID 59428418, compound

https://huagongshe.com/reaction/503960

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 66876536HCID 66876536—
SolventDichloromethaneHCID 6344—
ProductHCID 59428418HCID 59428418—

Reaction Steps

3-[2-Ethoxycarbonyl-4-(3-fluoro-benzenesulfonyl)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester (71 mg, 0.149 mmol) was dissolved in 2 ml of CH2Cl2. TFA (0.5 ml) was added and the mixture was stirred for 4 hours. The solution was concentrated under reduced pressure to give 5-(3-Fluoro-benzenesulfonyl)-2-pyrrolidin-3-yl-benzoic acid ethyl ester, MS (M+H)=378.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07776910B2
Source datasetuspto-grants-2010_08
ORD IDord-36cc75e1977f4416ab0bdab468640cc1
Source noteuspto-grants-2010_08