HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18412524, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | 3-Methyl-2-[2-(4-cyanophenyl)ethyl]-imidazo[1.2-a]pyridin-7-yl-carboxylic acid-n-(2-pyridyl)-n-(2-methoxycarbonylethyl)-amide-hydrochloride | HCID 18412601 | — |
| Reactant | Ethyl acetate ethanol ammonia | HCID 86587043 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 18412524 | HCID 18412524 | 53% |
Reaction Steps
Prepared analogously to Example 1 from 3-methyl-2-[2-(4-cyanophenyl)ethyl]imidazo[1,2-a]pyridin-7-yl-carboxylic acid-N-(2-pyridyl)-N-(2-methoxycarbonylethyl)amide hydrochloride and ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 53% of theory, C28H30N6O3 (498.59); Rf value: 0.42 (silica gel; ethyl acetate/ethanol/ammonia=50:45:5); EKA mass spectrum: (M+H)+=499; (M+2Na)++=272; (M+H+Na)++=261; (M+2H)++=250.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-7ac71ec04e984905bd065676e817b09d |
| Source note | uspto-grants-2004_03 |