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HRID50404

反应详情

EQUATION

反应方程式

HRID 50404 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1cnc(C(=N)N)cn1)n2C)c1ccccn1.Cl
HCID18412599

未命名化合物

PRODUCTS

生成物

1
结构：Cn1c(CNc2cnc(C(=N)N)cn2)nc2cc(C(=O)N(CCC(=O)O)c3ccccn3)ccc21
HCID18412381

未命名化合物

收率 11%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Prepared analogously to Example 26 from 1-methyl-2-[N-(2-amidinopyrazin-5-yl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 11% of theory, C23H23N9O3 (473.5); Rf value: 0.55 (Reversed Phase silica gel RP-8; 5% saline solution/methanol=6:4); EKA mass spectrum: (M+H)+=474; (M+H+Na)+=496.6.