Sodium Hydroxide → HCID 18412381, compound

Participants

Reaction Steps

Prepared analogously to Example 26 from 1-methyl-2-[N-(2-amidinopyrazin-5-yl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 11% of theory, C23H23N9O3 (473.5); Rf value: 0.55 (Reversed Phase silica gel RP-8; 5% saline solution/methanol=6:4); EKA mass spectrum: (M+H)+=474; (M+H+Na)+=496.6.

Provenance & Evidence