HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70203590, compound → HCID 72296181, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70203590 | HCID 70203590 | — |
| Reactant | HCID 86632081 | HCID 86632081 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 72296181 | HCID 72296181 | 14.2% |
Reaction Steps
In a manner similar to the method described in Example 1e, E/Z-6-chloro-3-[5-chloro-2-(1-methoxycarbonyl-1-methyl-ethoxy)-benzylidene]-2-oxo-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester (3 g, 5.94 mmol) was reacted with 1-(2,3-difluoro-6-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene (18 mmol) in toluene to give the title compound as a white solid (510 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07776875B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-48d605ba1cc54632b1209b6b6d2dfd1a |
| Source note | uspto-grants-2010_08 |