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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 504547Generated: November 2, 2026

HCID 70203590, compound → HCID 72296181, compound

https://huagongshe.com/reaction/504547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70203590HCID 70203590—
ReactantHCID 86632081HCID 86632081—
SolventTolueneHCID 1140—
ProductHCID 72296181HCID 7229618114.2%

Reaction Steps

In a manner similar to the method described in Example 1e, E/Z-6-chloro-3-[5-chloro-2-(1-methoxycarbonyl-1-methyl-ethoxy)-benzylidene]-2-oxo-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester (3 g, 5.94 mmol) was reacted with 1-(2,3-difluoro-6-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene (18 mmol) in toluene to give the title compound as a white solid (510 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07776875B2
Source datasetuspto-grants-2010_08
ORD IDord-48d605ba1cc54632b1209b6b6d2dfd1a
Source noteuspto-grants-2010_08