HCID 136331532, compound → HCID 136331531, compound

HRID 504973Notes

Reaction equation

HRID 504973 reaction equation
[NH2:1][C:2]1[NH:11][C:10](=[O:12])[C:9]2[C:4](=[N:5][CH:6]=[C:7]([CH2:13][NH:14][C:15]3[CH:96]=[CH:95][C:18]([C:19]([NH:21][CH:22]([C:92]([OH:94])=[O:93])[CH2:23][CH2:24][C:25](=[O:91])[NH:26][CH2:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][O:33][CH2:34][CH2:35][O:36][CH2:37][CH2:38][CH2:39][NH:40][C:41]4[C:44](=[O:45])[C:43](=[O:46])[C:42]=4[NH:47][CH2:48][CH2:49][O:50][CH2:51][CH2:52][O:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][O:59][CH2:60][CH2:61][O:62][CH2:63][CH2:64][O:65][CH2:66][CH2:67][O:68][CH2:69][CH2:70][O:71][CH2:72][CH2:73][O:74][CH2:75][CH2:76][O:77][CH2:78][CH2:79][O:80][CH2:81][CH2:82][NH:83]C(=O)OC(C)(C)C)=[O:20])=[CH:17][CH:16]=3)[N:8]=2)[N:3]=1>FC(F)(F)C(O)=O>[NH2:1][C:2]1[NH:11][C:10](=[O:12])[C:9]2[C:4](=[N:5][CH:6]=[C:7]([CH2:13][NH:14][C:15]3[CH:16]=[CH:17][C:18]([C:19]([NH:21][CH:22]([C:92]([OH:94])=[O:93])[CH2:23][CH2:24][C:25](=[O:91])[NH:26][CH2:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][O:33][CH2:34][CH2:35][O:36][CH2:37][CH2:38][CH2:39][NH:40][C:41]4[C:44](=[O:45])[C:43](=[O:46])[C:42]=4[NH:47][CH2:48][CH2:49][O:50][CH2:51][CH2:52][O:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][O:59][CH2:60][CH2:61][O:62][CH2:63][CH2:64][O:65][CH2:66][CH2:67][O:68][CH2:69][CH2:70][O:71][CH2:72][CH2:73][O:74][CH2:75][CH2:76][O:77][CH2:78][CH2:79][O:80][CH2:81][CH2:82][NH2:83])=[O:20])=[CH:95][CH:96]=3)[N:8]=2)[N:3]=1

Participants

3

Reactant 1

HCID 136331532HCID 136331532, compound

Product 1

HCID 136331531HCID 136331531, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

0.3 g of 18-[(4-{[(2-amino-4-oxo-3,4-dihydro-6-pteridinyl)methyl]amino}benzoyl)amino]-1-({2-[(39,39-dimethyl-37-oxo-3,6,9,12,15,18,21,24,27,30,33,38-dodecaoxa-36-azatetracont-1-yl)amino]-3,4-dioxo-1-cyclobuten-1-yl}amino)-15-oxo-4,7,10-trioxa-14-azanonadecan-19-oic acid is solubilized in 0.3 ml of trifluoroacetic acid.

Sources & evidence

ORD record
ord-7d4063029c984af581ff93321a7a899d
Source dataset
uspto-grants-2010_08
Patent number
US07780953B2

Reaction notes

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