Water → HCID 86761159, compound

Participants

Reaction Steps

3 g of tert-butyl 15-[(tert-butoxycarbonyl)amino]-1-(9H-fluoren-9-yl)-12-hydroxy-3-oxo-2,11,13-trioxa-4-aza-12-phosphahexadecan-16-oate 12-oxide are stirred in 0.62 ml of piperidine and 3 ml of water for 12 hours at ambient temperature. The reaction medium is filtered and the crystals obtained are washed twice with 50 ml of acetonitrile and then recrystallized from 100 ml of acetonitrile.

Provenance & Evidence