HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-4-nitro-1H-imidazole → 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid (1-benzyl-1H-imidazol-4-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-4-nitro-1H-imidazole | HCID 534138 | — |
| Reactant | 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid | HCID 21942986 | — |
| Product | 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid (1-benzyl-1H-imidazol-4-yl)-amide | HCID 86611454 | — |
Reaction Steps
1-Benzyl-4-nitro-1H-imidazole was reduced and coupled with 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid to afford the title compound; MS 470 m/z (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07781435B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-d75824e4737e40bbb25cceed3636abd0 |
| Source note | uspto-grants-2010_08 |