HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl (4-nitro-1-imidazolyl)acetate → (4-[2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoylamino]-imidazol-1-yl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl (4-nitro-1-imidazolyl)acetate | HCID 3103698 | — |
| Reactant | 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid | HCID 21942986 | — |
| Product | (4-[2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoylamino]-imidazol-1-yl)-acetic acid methyl ester | HCID 11582250 | — |
Reaction Steps
(4-Nitro-imidazol-1-yl)-acetic acid methyl ester was reduced and coupled with 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid to afford the title compound; MS 409.1 m/z (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07781435B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-2bb27ef17cb840fcaa3c1c412d5cd450 |
| Source note | uspto-grants-2010_08 |