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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 505048Generated: November 2, 2026

2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid → HCID 16113572, compound

https://huagongshe.com/reaction/505048

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acidHCID 21112802—
Reactant4-Nitro-1-[1-(4-trifluoromethyl-phenyl)-ethyl]-1H-imidazoleHCID 68463545—
ProductHCID 16113572HCID 16113572—

Reaction Steps

4-Nitro-1-[1-(4-trifluoromethyl-phenyl)-ethyl]-1H-imidazole was reduced and then coupled with 2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid (U.S. Ser. No. 11/078,898 filed Mar. 11, 2005) to afford the title compound: MS 521.5 m/z (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07781435B2
Source datasetuspto-grants-2010_08
ORD IDord-829b7c0f8cd249da9ee6b5a8787b2bd6
Source noteuspto-grants-2010_08