HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2-(Trifluoromethyl)phenyl]piperidine → (6-Chloro-1H-indol-3-yl)-[4-(2-trifluoromethyl-phenyl)-piperidin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2-(Trifluoromethyl)phenyl]piperidine | HCID 11413558 | — |
| Reactant | 6-chloro-1H-indole-3-carboxylic acid | HCID 18453235 | — |
| Product | (6-Chloro-1H-indol-3-yl)-[4-(2-trifluoromethyl-phenyl)-piperidin-1-yl]-methanone | HCID 59429661 | — |
Reaction Steps
Following general procedure I, the coupling of (commercially available) 4-(2-trifluoromethyl-phenyl)-piperidine (described herein) with 6-chloro-1H-indole-3-carboxylic acid gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07781436B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-93e272b46d1e42389a8ff2da02ff9713 |
| Source note | uspto-grants-2010_08 |