Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 505158Generated: October 30, 2026

Hydrochloric Acid → HCID 66743468, compound

https://huagongshe.com/reaction/505158

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 59429634HCID 59429634—
SolventMethanolHCID 887—
ProductHCID 66743468HCID 6674346899.4%

Reaction Conditions

Temperature50 °C

Reaction Steps

A mixture of 0.085 g (0.17 mmol) 10-[4-(2-methoxy-phenyl)-piperidine-1-carbonyl]-3,4-dihydro-1H-pyrazino[1,2-a]indole-2-carboxylic acid tert-butyl ester and 1.4 ml of a 1.25 M solution of hydrochloric acid (1.7 mmol) in methanol was stirred for 15 min at 50° C. The reaction mixture was concentrated in vacuo to give the title compound (0.072 g, 97%) as a light yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07781436B2
Source datasetuspto-grants-2010_08
ORD IDord-9543c91472a843a0a522967994f085f7
Source noteuspto-grants-2010_08