HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 505158Generated: October 30, 2026
Hydrochloric Acid → HCID 66743468, compound
https://huagongshe.com/reaction/505158
Participants
| Role | Name | HCID | Charge |
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| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59429634 | HCID 59429634 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66743468 | HCID 66743468 | 99.4% |
Reaction Steps
A mixture of 0.085 g (0.17 mmol) 10-[4-(2-methoxy-phenyl)-piperidine-1-carbonyl]-3,4-dihydro-1H-pyrazino[1,2-a]indole-2-carboxylic acid tert-butyl ester and 1.4 ml of a 1.25 M solution of hydrochloric acid (1.7 mmol) in methanol was stirred for 15 min at 50° C. The reaction mixture was concentrated in vacuo to give the title compound (0.072 g, 97%) as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07781436B2 |
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| Source dataset | uspto-grants-2010_08 |
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| ORD ID | ord-9543c91472a843a0a522967994f085f7 |
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| Source note | uspto-grants-2010_08 |
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