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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 505332Generated: October 30, 2026

Methyl iodide → HCID 178503342, compound

https://huagongshe.com/reaction/505332

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantHCID 86608957HCID 86608957—
SolventAcetoneHCID 180—
SolventDiethyl EtherHCID 3283—
ProductHCID 178503342HCID 17850334294%

Reaction Steps

Methyl iodide (0.30 ml, 4.86 mmol) was added to a suspension of 6-chloro-4-methyl-3,4-dihydro-1H-quinazoline-2-thione (345 mg, 1.62 mmol) in acetone (4.8 ml). The mixture was stirred for 2 hours (r.t.), diluted with diethyl ether and the title compound (538 mg, 94%) was isolated from the reaction mixture by filtration.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07781441B2
Source datasetuspto-grants-2010_08
ORD IDord-fe297195786f4c99aad836d48acca15c
Source noteuspto-grants-2010_08