反应详情

5 g of methyl 5-chloro-6-(2,4-dichlorophenyl)-7-isopropylaminopyrazolo[1,5-a]pyrimidine-3-carboxylate were dissolved in 75 ml of 1,4-dioxane, and 75 ml of 2 N aqueous potassium hydroxide solution were added. The mixture was stirred at room temperature for 15 h (monitored by TLC) and then introduced into 1 N hydrochloric acid. The precipitated solid was filtered off with suction.

1. filtrationThe precipitated solid was filtered off with suction