1-Methylpiperazine → HCID 10316903, compound

HRID 505625Notes

Reaction equation

HRID 505625 reaction equation
Cl[CH2:2][C:3]1[C:4]2[C:9]([N:10]3[S:18](=[O:20])(=[O:19])[C:17]4[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=4)[C:11]=13)=[CH:8][CH:7]=[CH:6][CH:5]=2.[CH3:21][N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1>>[CH3:21][N:22]1[CH2:27][CH2:26][N:25]([CH2:2][C:3]2[C:4]3[C:9]([N:10]4[S:18](=[O:20])(=[O:19])[C:17]5[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=5)[C:11]=24)=[CH:8][CH:7]=[CH:6][CH:5]=3)[CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 68639198HCID 68639198, compound

Product 1

HCID 10316903HCID 10316903, compound

Procedure

Alternatively, 10-Chloromethyl-5-thia-4b-aza-indeno[2,1-a]indene-5,5-dioxide (D37), may be treated with N-methylpiperazine according to the method as described under Description 1, to obtain the above said compound. Melting range (° C.): 121-125; IR spectra (cm−1): 1180, 1289, 1336, 1439; Mass (m/z): 368, 370 (M+H)+; 1H-NMR (ppm): 2.42 (s, 3H), 2.73-2.83 (bs, 8H), 3.88 (s, 2H), 7.22-8.07 (m, 8H).

Workup

  1. customto obtain the above said compound

Sources & evidence

ORD record
ord-ff302b276dd148a2a984e48b4015c9bd
Source dataset
uspto-grants-2010_08
Patent number
US07781476B2

Reaction notes

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