反应详情

温度

60 °C

The above-obtained 2-(benzyloxymethyl)-4,6-bis(methoxymethoxy)-N-phenylbenzamide (18 mg, 0.043 mmol) was dissolved in ethanol (4 mL) and the obtained solution was added with concentrated hydrochloric acid (0.10 mL) followed by stirring at 60° C. for 1 hour. The reaction mixture was concentrated under reduced pressure and the residue was purified by preparative thin-layer chromatography (chloroform/methanol=20/1) to obtain Compound 1 (14 mg, 92%).

1. concentrationThe reaction mixture was concentrated under reduced pressure
2. customthe residue was purified by preparative thin-layer chromatography (chloroform/methanol=20/1)