HRID505833

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O.O=S(=O)(O)O

HCID441374

Kanamycin A sulfate

C18H38N4O15S

PRODUCTS

生成物

结构：NC[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@@H](O)[C@H](O)[C@H]1O

HCID11274101

未命名化合物

收率 113.6%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

Kanamycin sulfate (20.0 g) was dissolved in 200 mL of water. This was loaded on a column prepared with 400 g of AMBERLITE IRA-140 resin (6.4 cm×17.5 cm). The column was eluted with water, and the appropriate fractions were collected and lyophilized to give 18.9 g of kanamycin A (free base) (18).

WORKUP

后处理

customprepared with 400 g of AMBERLITE IRA-140 resin (6.4 cm×17.5 cm)
washThe column was eluted with water
customthe appropriate fractions were collected