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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 50643Generated: October 29, 2026

Hydrochloric Acid → (1R-trans)-2-(3,4-Difluorophenyl)-N-methylcyclopropanamine, Hydrochloride

https://huagongshe.com/reaction/50643

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant(1r-trans)-n-[2-(3,4-Difluorophenyl)cyclopropyl]-n-methylacetamideHCID 69886212—
Product(1R-trans)-2-(3,4-Difluorophenyl)-N-methylcyclopropanamine, HydrochlorideHCID 131724387—

Reaction Steps

A solution of the product from step b) (443 mg) in 4M HCl (10 ml) was refluxed for 8 h. The solvent was removed in vacuo to give the sub-title compound (357 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06713483B1
Source datasetuspto-grants-2004_03
ORD IDord-7bc1f35465134208be37a322434d9189
Source noteuspto-grants-2004_03