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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 50644Generated: October 27, 2026

2,3-Dihydroxybutanedioate → (1r-trans)-n-[2-(4-Methoxyphenyl)cyclopropyl]acetamide

https://huagongshe.com/reaction/50644

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DihydroxybutanedioateHCID 3806114—
Reactant(1R,2S)-2-(4-methoxyphenyl)cyclopropanamineHCID 10442008—
Product(1r-trans)-n-[2-(4-Methoxyphenyl)cyclopropyl]acetamideHCID 69887991—

Reaction Steps

The sub-title compound was prepared according to the method of Example 4, step a) from (1R-trans)-2-(4-methoxyphenyl)cyclopropanamine, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (prepared as described in W09905143) to give a white solid (655 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06713483B1
Source datasetuspto-grants-2004_03
ORD IDord-3dd25e56c5904d0aa5c5dba4d6757c65
Source noteuspto-grants-2004_03