HCID 44407298, compound → HCID 67153148, compound

Participants

Reaction Steps

Pd/C (10%, 10.0 mg) was added to a solution of 1-((2E)-4-{4-[2-tert-butyl-6-(trifluoro-methyl)pyrimidin-4-yl]piperazin-1-yl}-2-methylbut-2-enyl)-3,4-dihydroquinolin-2(1H)-one (0.08 mmol, 49.99 mg) from example 12 in methanol (10 ml), and hydrogenation was then carried out at room temperature for 12 hours. 11.10 mg of the title compound were obtained.

Provenance & Evidence