Hydrochloric Acid → HCID 22063499, compound

HRID 506557Notes

Reaction equation

HRID 506557 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([NH:12]C=O)([CH3:11])[CH3:10])=[C:4]([CH3:15])[CH:3]=1.Cl>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([NH2:12])([CH3:10])[CH3:11])=[C:4]([CH3:15])[CH:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22063470HCID 22063470, compound

Product 1

HCID 22063499HCID 22063499, compound

Procedure

In order to prepare the amine, 27.0 g (130 mmol) of N-[2-(4-fluoro-2-methylphenyl)-1,1-dimethylethyl]formamide is reacted as described in the method for Example 10(c). White solid. Yield: 15.5 g (55%, hydrochloride); melting point: 277° C.-280° C.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-81721c8148834451ac3283b8406651fb
Source dataset
uspto-grants-2010_08
Patent number
US07786111B2

Reaction notes

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