Benzaldehyde → HCID 178526787, compound

HRID 506585Notes

Reaction equation

HRID 506585 reaction equation
[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][C:5]([N+:9]([O-:11])=[O:10])=[CH:4][N:3]=1.[CH:12](=O)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>[N+](C1C=CC=CC=1)([O-])=O>[N+:9]([C:5]1[CH:6]=[C:7]2[N:8]=[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[NH:1][C:2]2=[N:3][CH:4]=1)([O-:11])=[O:10]

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 34801515-Nitropyridine-2,3-diamine

Product 1

HCID 178526787HCID 178526787, compound

Reagents, catalysts & solvents 1

HCID 7416NitrobenzeneSolvent

Procedure

14.05 g 2,3-diamino-5-nitropyridine and 9.68 g benzaldehyde in 250 ml nitrobenzene were heated to 140-150° C. for 15 hrs. The solvent is removed by vacuum distillation and the residue is dispersed in ethyl acetate, filtered, and the filter residue washed thoroughly with ethyl acetate.

Workup

  1. customThe solvent is removed by vacuum distillation
  2. additionthe residue is dispersed in ethyl acetate
  3. filtrationfiltered
  4. washthe filter residue washed thoroughly with ethyl acetate

Sources & evidence

ORD record
ord-738b272c602f4b0bbe6feb48df40569c
Source dataset
uspto-grants-2010_08
Patent number
US07786113B2

Reaction notes

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