HuagongsheHuagongshe Chemistry Print Report · For research reference only
Eltoprazine → 3-{4-[4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Eltoprazine | HCID 65853 | — |
| Reactant | 3-(4-Chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one | HCID 68463623 | — |
| Product | 3-{4-[4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)-piperazin-1-yl]-butyl}-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one | HCID 68467251 | — |
Reaction Steps
The title compound is prepared according to process H by applying processing method 1 starting from 3-(4-chlorobutyl)-3-ethyl-6-fluoro-1,3-dihydro-2H-indol-2-one and 4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07786129B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-d7d3e10705034d2cac4da829d7520a56 |
| Source note | uspto-grants-2010_08 |