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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 506923Generated: November 3, 2026

1-(4-Fluorophenyl)piperazine → 3-ethyl-3-{4-[4-(4-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-one

https://huagongshe.com/reaction/506923

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)piperazineHCID 75260—
Reactant3-(4-Chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-oneHCID 67040633—
Product3-ethyl-3-{4-[4-(4-fluorophenyl)-piperazin-1-yl]-butyl}-1,3-dihydro-2H-indol-2-oneHCID 24854187—

Reaction Steps

The title compound is prepared according to process H by applying processing method 1 starting from 3-(4-chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 1-(4-fluorophenyl)-piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07786129B2
Source datasetuspto-grants-2010_08
ORD IDord-5d58094e2c06489c93b3f9ec0962c4fb
Source noteuspto-grants-2010_08