1-(4-Fluorophenyl)piperazine → HCID 68467849, compound

HRID 506933Notes

Reaction equation

HRID 506933 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([Cl:11])[CH:10]=1)[NH:7][C:6](=[O:12])[C:5]2([CH2:15][CH2:16][CH2:17][CH2:18]Cl)[CH2:13][CH3:14].[F:20][C:21]1[CH:26]=[CH:25][C:24]([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)=[CH:23][CH:22]=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([Cl:11])[CH:10]=1)[NH:7][C:6](=[O:12])[C:5]2([CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH2:18][N:30]1[CH2:29][CH2:28][N:27]([C:24]2[CH:23]=[CH:22][C:21]([F:20])=[CH:26][CH:25]=2)[CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 752601-(4-Fluorophenyl)piperazineHCID 67500192HCID 67500192, compound

Product 1

HCID 68467849HCID 68467849, compound

Procedure

The title compound is prepared according to process H by applying processing method 1 starting from 5,7-dichloro-3-(4-chlorobutyl)-3-ethyl-1,3-dihydro-2H-indol-2-one and 4-(4-fluoro-phenyl)-piperazine.

Sources & evidence

ORD record
ord-742383767d794cf49a3350d9b508caca
Source dataset
uspto-grants-2010_08
Patent number
US07786129B2

Reaction notes

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